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Computational evidence of new putative allosteric sites in the acetylcholinesterase receptor

Mental health disorders are common and affect around 16% of men in the United States ( Some research suggests that people with mental health disorders like depression have lower blood folate levels than people without depression ( For example, a large review of 43 studies including over 35,000 people found that those with depression tended to have lower folate levels and typically consumed less folate through their diet than people without depression ( Another review that included 6 studies and 966 people found that taking folic acid supplements alongside antidepressant medication could reduce symptoms of depression significantly more than taking an antidepressant medication alone ( That said, more research in the area of folic acid and treatment for mental health disorders such as depression is needed before making recommendations

Given that supplements are concentrated versions of the vitamin, its unclear if foods would have the same effect

If your levels aren't improving with supplementation, discuss potential underlying health conditions, such as GI disorders, and potential medication interactions (such as antibiotics, H2 blockers, and PPIs), with your doctor