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The percentages from the Phase 2 retatrutide trial and the Phase 3 tirzepatide trials look different, but those trials enrolled different populations under different protocols

Its sequence is Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, with a molecular weight of approximately 1419 g/mol and CAS number 137525-51-0

Receptor proximal assays can include cAMP response measurements, calcium flux assays where applicable, recruitment assays that track pathway engagement, and internalization or trafficking readouts that inform residence and persistence