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106 Additionally, Tanzeum is not suitable for treating type 1 diabetes or diabetic ketoacidosis, related to its pharmacological action and target disease

While the MIA model was initially linked to only IL-6, nearly a decade of research has revealed that a more robust immune response occurs within the MIA model [172]

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Whether retatrutide's glucagon receptor agonism provides additive cardiovascular benefit beyond what GLP-1 and GIP activation deliver is an important question that dedicated cardiovascular outcomes trials (CVOTs) within the TRIUMPH program may eventually answer