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UTMD-mediated IGF-1 transfection enhanced inflammatory cell infiltration, reduced scar tissue formation, and improved maximum load, stiffness, and ultimate stress at weeks 2 and 8 ( Collectively, these studies highlight the significant therapeutic potential of IGF-1 in tendon healing across various animal models

IGF-1 LR3 is a modified analog designed for extended activity and reduced binding affinity to IGF-binding proteins , allowing prolonged signaling in research models

Mineral trioxide aggregate upregulates odonto/osteogenic capacity of bone marrow stromal cells from craniofacial bones via JNK and ERK MAPK signalling pathways

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