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Although HbA 1c is an indicator of mean glucose, it does not inform glycaemic variability and hypoglycaemia and, therefore, is inappropriate as the only method of glucose evaluation in type 1 diabetes [68, 69]
Korsakova, 114(7), 1722
contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 Risk of diabetic retinopathy complications in patients with pre-existing retinopathy Potential for acute kidney injury, particularly related to dehydration Caution or avoidance in severe gastroparesis or severe gastrointestinal disease Suicidality warning for weight-management indications (Wegovy, Saxenda) Potential for altered absorption of oral medications due to delayed gastric emptying In older adults with cognitive impairment, medication adherence may be challenging, and gastrointestinal side effects could lead to dehydration or nutritional deficiencies
AOD-9604 is a synthetic peptide derived from human growth hormone (hGH), specifically from amino acids 177-191 of the hGH molecule
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