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estrogen upregulates the PRL gene, which directly increases prolactin synthesis Prolactin inhibits testosterone release from the pituitary Using a dopamine agonist helps decrease prolactin-producing cells If youre concerned about high prolactin, eliminate things that increase it, like casein (milk protein) or gluten, which are mu-opioid receptor agonists in the gut 00:24:23 Social Relationships & Hormones, Tool: Planning for Crisis Just like women who spend lots of time together have their menstrual cycles align, theres tons of pheromonal and hormonal crosstalk (including prolactin) between men and women Spending 100% of time together is why its hard to work and live together

Essential GLP-1 Progress Metrics Universal Tracking (All GLP-1 Medications) Core Metrics for Every GLP-1 User Injection Adherence: Track timing, doses, and consistency Side Effects: Monitor GLP-1-specific symptoms and patterns

Kochhar GS, Khataniar H, Jairath V, Farraye FA, Desai A

In the SURMOUNT-1 trial, for example, individuals taking a 5mg weekly dose experienced 15.0% weight loss over 72 weeks