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24 With respect to this, the negative association between frequency of the cSHMT -C1420T variant and latitude documented in this study may indicate that activity of the de novo thymidylate synthesis pathway is increasingly impaired in populations exposed to higher UVR, but the burden of this variant is unclear due to mSHMT likely maintaining cSHMT activity in such cases

Epigenetic CD177 silencing in one neutrophil subset and random monoallelic expression in another neutrophil subset yields two distinct CD177 neg /mPR3 low and CD177 pos /mPR3 high cell populations (148)

doi: 10.3389/fphys.2018.00477 42 LehrerSRheinsteinPH

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