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Description

Retrieved from Dyatlova, N., Tobarran, N

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Description 5-Amino-1MQ: Investigating the Bioenergetics of NNMT Inhibition 5-Amino-1MQ is a highly selective, membrane-permeable molecule designed to address metabolic dysfunction at the enzymatic level

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Seahorse XP extracellular analysis, Liquid Chromatography/ Mass Spectrophotometry (LC/MS), and 2,7- and Dichlorofluoresin diacetate (DCFDA) assay were used to assess the effects of metformin on cellular bioenergetics, redox status, and redox-related metabolites

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Both approaches produce modest effects compared to actual GLP-1 medications

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