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Turunen M, Appelkvist EL, Sindelar P, Dallner G
Risks of Improper IGF-1 LR3 Dosing Because IGF-1 stimulates growth pathways, excessive or unsupervised dosing may increase risks, including: Hypoglycemia (low blood sugar) Edema Joint discomfort Nerve compression symptoms Potential overstimulation of mitogenic pathways IGF-1 signaling is also involved in cellular proliferation
Despite the development of GLP-1 monoagonists, new peptides that combine the pharmacology of GLP-1 with other gut peptides increase the efficacy of these agonists while reducing their dose-related gastrointestinal side effects
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