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Advanced LC-MS Techniques in GLP-1 Peptide Drug Characterization Modern LC-MS Characterization of GLP-1 Peptides increasingly relies on advanced analytical technologies that offer greater sensitivity and deeper structural insight

A notable limitation of these agents is the need for continuous treatment, as discontinuation has been associated with rebound weight gain (56)

Perspective on the Rx Pipeline: Diabetes and GLP-1 Agonists Situation Summary Initial therapy for individuals with T2DM who are at high risk for CVD, heart failure (HF) and/or chronic kidney disease is metformin and a glucagon-like peptide 1 (GLP-1) or sodium glucose transporter ligand 2 (SGLT-2)

Unlike Mounjaro, it does not target GIP receptors