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Results: Berberine reduced renal injury in STZ-induced DN rat model, as evidenced by the decrease in fasting blood glucose, ratio of kidney weight to body weight, 24-h urinary protein, serum creatinine, and blood urine nitrogen
English search terms included: diabetic kidney disease OR diabetic nephropathy OR DKD OR DN, combined with gut microbiota OR gut microbiome OR intestinal flora OR intestinal microbiota, dietary OR nutrition OR diet OR nutritional intervention, phytochemical OR natural product OR bioactive compound OR functional food, amino acid metabolism OR metabolite OR metabolomics, gut-liver axis OR gut-kidney axis OR enterohepatic axis, short-chain fatty acids OR SCFAs, and probiotics OR prebiotics OR synbiotics. Inclusion criteria were: (1) studies addressing the associations among DKD, gut microbiota, nutritional intervention, and natural bioactive compounds
Self-reported changes in taste were not tied to changes in BMI
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