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This plays a crucial role in regulating the basal expression and antioxidant induction of NQO1 and other detoxification genes [41]

At the same time, mTORC1 in active state inhibits autophagy by suppressing activity of the Unc-51-like kinase 1 (ULK1) and initiates protein biosynthesis via phosphorylation of the main mRNA translation regulators, such as proteins of the 4E-BP group inhibiting protein synthesis initiation factor eIF4E [27]

The name AHK stands for alanine, histidine, and lysine, the three amino acids in its chain

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