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593 Current research on DN and its associated complications remains limited in terms of comprehensive management and multidisciplinary collaboration, and the interactions between different complications remain poorly understood

Activation of pancreatic enzymes exacerbates necrosis, damages endothelial cells, and induces edema, hypoxia, and organ failure [19,20,21]

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Finally, we searched for the plausible negative impacts of GLP1R agonists as the addiction alternatives by primary and deep in silico analyses and introduced multiple findings supporting GLP1R agonists, which can induce depression phenotypes