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By inhibiting this enzyme, NAD+ levels rise within cells, leading to enhanced energy metabolism , lipid breakdown , and mitochondrial activation

Existing treatments primarily fall into two categories, ChEIs and NMDA receptor antagonists

Another explanation for the decrease in punctuate NCOA4 staining is that while NCOA4 might be located in synapses in a control setting, and these synapses are lost in AD [45]