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The honest answer has three parts

She noted that her hair had thinned severely due to a compounding history of Anavar (a DHT-derivative steroid) usage, acute autoimmune thyroiditis, and rapid weight loss induced by the GLP-1 receptor agonist retatrutide

Hence, increased DA signaling might contribute to mPFC hyperexcitability as reported here and previously reported hyperactive DA neurons in the ventral tegmental area [4, 5]

Anxiety symptoms often emerge or worsen during the perimenopausal period and can be both a result of the hormonal fluctuations as well as a response to the psychosocial stresses associated with aging, such as changes in family dynamics, career, and overall self-identity [41,42,56]