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Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

Dillon JS, Tanizawa Y, Wheeler MB, Leng XH, Ligon BB, Rabin DU, Yoo-Warren H, Permutt MA, and Boyd AE, 3rd

These alterations of renal energy and substrate metabolism may result from inherent abnormalities, including genetic defects, attempts of the kidneys to respond to environmental stressors, such as high-salt intake, or a combination of internal and external factors