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Cold medication directly from refrigeration may potentially intensify discomfort for some patients

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More future-facing interest: researchers tend to be most excited by compounds that expand the mechanism rather than simply optimize a known one

Symptoms Lower and upper tract infections can cause one or more of the following symptoms: Unusually frequent urination An intense urge to urinate Pain, discomfort or a burning sensation during urination Pain, pressure or tenderness in the area of the bladder (midline, above or near the pubic area) Urine that looks cloudy, or smells foul or unusually strong Fever, with or without chills Nausea and vomiting Pain in the side or mid-to-upper back Waking from sleep to pass urine Bedwetting in a person who has usually been dry at night Diagnosis Your doctor will ask you about your symptoms and whether you have had a urinary tract infection before