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This is an important context for researchers evaluating the compounds evidence base

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In more rare yet severe cases, you may experience: Itching or a feeling of swelling all over the body Muscle cramps and weakness Upset stomach and urinary problems Swelling in the ankles or feet Unusual tiredness Irregular heartbeat or trouble breathing If these side effects occur, consult your healthcare provider before continuing B12/MIC

Ototoxin exposure times were selected based on previous work (Ou et al., Hair cell assessment Survival of lateral line hair cells was assessed by vital dye labeling in live fish