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Moreover, small molecule GLP-1s like orforglipron have demonstrated superiority to semaglutide in late-stage clinical trials

These abnormalities are often accompanied by left ventricular hypertrophy, left atrial dilation, and subtle systolic dysfunction despite preserved ejection fraction, as well as extracardiac manifestations such as pulmonary hypertension and skeletal muscle impairment [22]

Enhances Health Markers Semaglutide has also been shown to significantly enhance several key health markers

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