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Back to Journals Diabetes, Metabolic Syndrome and Obesity Volume 12 Dual GIPGLP1-Receptor Agonists In The Treatment Of Type 2 Diabetes: A Short Review On Emerging Data And Therapeutic Potential Authors Bastin M , Andreelli F Received 12 May 2019 Accepted for publication 17 August 2019 Published 30 September 2019 Volume 2019:12 Pages 19731985 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Konstantinos Tziomalos Marie Bastin, Fabrizio Andreelli Diabetology-Metabolism Department, Sorbonne Universit, ICAN, Assistance Publique Hpitaux de Paris, Piti-Salptrire Hospital, Paris, F-75013, France Correspondence: Fabrizio Andreelli Diabetology-Metabolism Department, Piti-Salptrire Hospital, 47-83 Boulevard de lHpital, Paris cedex 13, 75951, France Email [email protected] Abstract: The need for efficient and safe therapy to improve such metabolic diseases as obesity and type 2 diabetes mellitus is currently unmet

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260 In patients with UC, the Wnt/-catenin pathway is often abnormally activated, resulting in abnormal proliferation and differentiation of intestinal mucosal epithelial cells, which in turn triggers an inflammatory response and tissue damage

Different mechanisms create synergy