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The World Health Organization issued a medical-product alert in 2024 after falsified incretin injectables turned up across the Americas and Europe

1, 2 Diet and life-style modification represent the first-line treatment in the management of obesity, but as these often fail to provide sustainable weight loss, pharmaceutical intervention may be necessary for the achievement of long-term, clinically relevant weight loss

Inflammation is known to play a role in hormonal imbalances, and GLP-1s have been shown to reduce systemic inflammation, which may help alleviate symptoms like mood swings and metabolic issues commonly experienced

A fractional laser may also be effective