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Injection-Site Reactions As with any insulin or GLP-1 receptor agonistcontaining product, patients taking SOLIQUA 100/33 may experience injection-site reactions, including injection-site hematoma, pain, hemorrhage, erythema, nodules, swelling, discoloration, pruritus, warmth, and injection-site mass

The PBM then retains the difference between the MAC price they pay the pharmacy and the price the health plan pays, which is termed the spread. In a recent example of the pharmacy spread problem, two PBMs in Ohio reimbursed pharmacies $2.3 billion and billed Medicaid $2.5 billion for their generic and branded drugs, resulting in a spread of $200 million

Weight regain is possible if lifestyle and dietary changes are not maintained

It is a multi-agonist peptide, meaning it targets three important receptors in the body: GLP-1 (Glucagon-like peptide-1), GIP (Glucose-dependent insulinotropic polypeptide), and GCGR (Glucagon receptor)