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swelling in your feet or ankles Feeling short of breath (even with mild exertion), rapid weight gain Ketoacidosis (too much acid in the blood) nausea and/or vomiting accompanied by abdominal pain If you notice any of these symptoms while taking Janumet, seek medical attention immediately as they could indicate a potentially serious condition

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The calibration and validation results show that both in the control and the rd1 case, the model produces output for [GSH] and [GSSG] approximating trends in the experimental data, and there is notable uncertainty in the estimated parameters