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Weeks 13 onward: 12mg once weekly (target maintenance dose for maximum efficacy)

Prescription GLP-1s work by acting as super sticky versions of gut hormones and that bind the same receptors that stimulate key pathways like appetite suppression and blood sugar regulation but much more powerfully and for longer periods (days or even weeks)

Trial design and data sharing of standardized protocol elements and outcomes should be encouraged to support reproducibility of outcomes and meta-analysis

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