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Received: Published: Version of record: Issue date: DOI:

R., Donohoe, M., Ellard, S

Forecast: Future-focused physicians will target stress both subjective and objective, measured through cortisol patterns, HRV, and other markers as a foundational element of whole-person patient care

The single-pill formulation of AXS-05 (recommended dosage, twice daily) is likely to be advantageous for adherence, as single-pill regimens have demonstrated substantially better adherence and persistence in other chronic diseases than multi-treatment regimens [138,139,140]