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It was found that the treatment cream inhibited the inflammatory pathways by instigating the reduced expression of pro-inflammatory cytokines (IL-17 and IFN- ) together with increased anti-inflammatory cytokines (IL-10)

In fact, because the body doesnt store excess vitamin B12, supplementation is generally considered safe, even at large doses

The full implications of this for treatment duration recommendations will be addressed in formal prescribing guidance if and when the medication is approved

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