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Other common causes of cold sensitivity should also be considered, including iron-deficiency anaemia and vitamin B12 deficiency (particularly relevant for patients also taking metformin, which can reduce B12 absorption)

When deficient, you may feel chronically fatigued, no matter how much rest you get

A huge thank you to Dr MJ for sharing all of her worldly wisdom with us

however, this difference was not statistically significant.180 In a prospective cross-sectional study conducted by Sen et al181 involving 124 patients scheduled for elective surgery under general anesthesia, gastric ultrasound revealed retained gastric contents in 35 of 62 patients receiving GLP-1RAs therapy versus 12 of 62 controls, despite adherence to the current fasting guidelines in both cohorts