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Role of ferroptosis in PD Ferroptosis is regulated by multiple interconnected pathways, including the GPX4/GSH system, iron and lipid metabolism, the NRF2 signaling pathway and mitochondrial function, in PD (Fig

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This evidence highlights the importance of PTM in inflammatory autoimmune conditions and their potential use as biomarkers for early diagnosis and disease stratification

The authors conclude that past respiratory disorders maximally contribute to IPF risk, followed by known IPF comorbidities, metabolic diseases, cardiovascular abnormalities, and diseases of the eye, with the overall pattern of the importance ranking substantially invariant across the sexes