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Li S, Zhao Q, Wang B et al (2018) Quercetin reversed MDR in breast cancer cells through down-regulating P-gp expression and eliminating cancer stem cells mediated by YB-1 nuclear translocation
Prolonged IGF-1 elevation may interfere with insulin signaling pathways, resulting in glucose metabolism disruption and increased diabetes risk. Clemmons, The Journal of Clinical Endocrinology & Metabolism Cell Overproliferation and Cancer Concerns IGF-1 promotes cell growth and replication , which is great for musclebut not ideal in individuals with: A history of cancer A family history of hormone-sensitive tumors Undiagnosed growths or cysts IGF-1 is considered mitogenic , meaning it encourages cell division
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