Topical Treatments for Melasma and Their Mechanism of Action
BENEFITS OF GLUTATHIONE FOR SKIN HEALTH Glutathione reduces oxidative stress in the body to improve your overall complexion
J Pineal Res 56(1):97106 Parzych KR, Klionsky DJ (2014) An overview of autophagy: morphology, mechanism, and regulation
Topicals (proven brighteners) Vitamin C serum in the morning Niacinamide for tone and barrier Retinoid at night (started cautiously) Targeted pigmentation actives (alpha arbutin, tranexamic acid, kojic acid, azelaic acid) where indicated Hydroquinone in a planned, cycled course for melasma where appropriate, under supervision In-clinic A planned course of chemical peels (mandelic, glycolic, salicylic depending on skin type) For melasma specifically, sometimes specialty lasers or microneedling-RF in selected cases Lifestyle Sleep, hydration, antioxidants in diet Iron and vitamin D corrected if deficient Stop the at-home over-acid-stacking that brings most patients to dull, sensitised skin in the first place And, optionally glutathione If, after a foundation is in place, a patient still wants to try IV glutathione, we discuss honestly: Pharmaceutical-grade product, sourced and stored properly Medical supervision
