Epub ahead of print Seferovi PM, Coats AJS, Ponikowski P, Filippatos G, Huelsmann M, Jhund PS, Polovina MM, Komajda M, Seferovi J, Sari I, Cosentino F, Ambrosio G, Metra M, Piepoli M, Chioncel O, Lund LH, Thum T, De Boer RA, Mullens W, Lopatin Y, Volterrani M, Hill L, Bauersachs J, Lyon A, Petrie MC, Anker S, Rosano GMC (2020) European Society of Cardiology/Heart Failure Association position paper on the role and safety of new glucose-lowering drugs in patients with heart failure
A comprehensive approach to GLP-1 constipation relief should always include electrolyte optimization as a foundational step
Mechanisms and evidence bases are not interchangeable
While human clinical trials have not yet been completed, the existing data provides valuable insight into how the compound works and what effects it produces