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Vitamin B12 supplementation is available in several forms, including oral tablets, sublingual (dissolved under the tongue) preparations, nasal sprays, and intramuscular injections (commonly known as B12 shots)

Here, we reported an oligopeptide hydrogel that encapsulates cell-penetrating-peptide (CPP)-decorated curcumin-loaded nanoemulsions (Cur-CNEs) to enhance the skin penetration of curcumin for topical treatment of psoriasis