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While the first step of glutathione synthesis is restricted to chloroplasts in Arabidopsis and wheat, the second step is primarily confined to the cytosol (Noctor et al
In combination with diet and exercise, GLP-1 RAs medications may help people lose weightmore than 80% of patients with type 2 diabetes also have overweight or obesity, which means many patients could benefit from the dual effects
Senescent fibroblasts in diabetic wounds exhibit ferroptosis resistance due to defective ferritinophagy, but upregulating the expression of the ferritin autophagy-related molecule NCOA4 increases their susceptibility to ferroptosis and improves wound healing [81]
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