Sophie is clear on the boundary: nutrition doesn't cause MS, and it won't cure it
The RCTs were characterized by small numbers of enrolled patients, short duration of observation, concomitant use of IV and oral iron, adjustments in ESA dosage, high dropout rates, and uncertainty about specific ESA and/or iron dosing during the study
If its real, says Pearce, its probably very very rare and very low risk. Nevertheless, Pearce suggests that American clinicians will likely continue to follow prescribing guidelines for medical-legal reasons, if nothing else. Fortunately only a tiny minority of people are affected by this warning
The exposure in five of those studies was serum/plasma B12, while one study additionally investigated vitamin B12 intake [7] and one study investigated only vitamin B12 intake [12]