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Both routes have published evidence

Clinicians should also avoid or adjust therapy in individuals with active peptic ulcer disease due to theoretical choline-mediated increases in gastric volume and in those receiving levodopa, as pantothenic-acid derivatives may interfere with levodopa absorption

Functional GI Disorders Esophageal Functional chest pain Globus Functional heartburn Functional dysphagia Reflux hypersensitivity Functional dyspepsia Nausea and vomiting Postprandial distress syndrome (PDS) Epigastric pain syndrome (EPS) Cyclic vomiting syndrome (CVS) Belching disorders Cannabinoid hyperemesis syndrome (CHS) Rumination syndrome Bowel Disorders Irritable bowel syndrome (IBS) Functional constipation IBS with predominant constipation (IBS-C) Functional diarrhea IBS with predominant diarrhea (IBS-D) Functional abdominal bloating/distension IBS with mixed bowel habits (IBS-M) Opioid-induced constipation (OIC) Anorectal Disorders Proctalgia fugax Functional anorectal pain Functional defecation disorders Levator ani syndrome Dyssynergic defection Your provider will work with you to diagnosis your symptoms and determine the best treatment options which may include: Anti-motility medications Pro-motility medications Referral to physical therapy for pelvic floor dysfunction Biofeedback Referral to dietician Referral to counselor/psychiatrist App based tracking Better Control for Better Living 18 million Americans suffer from bowel incontinence Which means you are not alone