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However, efficient and targeted intra-articular gene delivery remains a considerable technical challenge, primarily due to the dense extracellular matrix (ECM) of cartilage, rapid clearance of joint fluid, and limited cellular uptake
Franz cell diffusion studies show real but low penetration, which depends heavily on the vehicle (liposomes, nanoemulsions)
I was really comfortable throughout the procedure and I am very happy with the initial results so cant wait to see the final result when healed
Therefore, early prophylactic treatment is necessary for improving the prognosis of CM patients
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