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The follow-on open-label extension published by Steven Grinspoon and colleagues in 2010 and 2012 confirmed that the VAT reduction was maintained through 52 weeks of continuous dosing and that patients who switched from placebo to active compound at week 26 caught up to the original treatment arm by week 52

In Vitro Addition of Epithalon peptide in telomerase-negative human fetal fibroblast culture induced expression of the catalytical subunit, enzymatic activity of telomerase, and telomere elongation, which can be due to reactivation of telomerase gene in somatic cells and indicates the possibility of prolonging life span of a cell population and of the whole organism [1]

Fix: swirl gently

10.1210/en.2003-0805 99 KempurajD.SelvakumarG