Hypersensitivity reactions Serious hypersensitivity reactions, including anaphylaxis and angioedema, have been reported with semaglutide Avoid use in patients with known hypersensitivity to semaglutide and use caution in patients with a history of reactions to other GLP-1 analogs Semaglutide antibodies Semaglutide can induce an immune response that leads to the production of anti-semaglutide antibodies, and in some cases, these antibodies cross-react with endogenous GLP-1 In trials, 2.9% of Wegovy-treated patients developed anti-semaglutide antibodies, and of these patients, 56% had antibodies that cross-reacted with endogenous GLP-1
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We did not propose to subject low volume diagnostic radiopharmaceutical APCs to the broader OPPS low volume policy, and we note that the low volume APC policy does not apply to APCs to which single drugs, biologicals, or radiopharmaceuticals are assigned, even if there is a low volume of claims for these items