More evidence in the form of high quality trials with better study design, larger sample size, and long-term follow-up is vital, before our patients are subjected to glutathione-based treatments
10.1007/s41030-023-00226-y 44 DuveK.PetakhP.KamyshnyiO
The review also covered three therapeutic research strategies: direct GSH depletion (leading to ferroptosis or enhanced chemotherapy sensitivity), indirect approaches targeting the tumour microenvironment, and prodrug strategies utilising elevated tumour GSH for drug activation
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