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After treated with L-carnitine, serum levels of IL-1, IL-6 and TNF-, and the skeletal muscle content of MuRF1, MaFbx, FOXO3, p-FOXO3a, Akt, p-Akt, p70S6K and p-p70S6K were measured
As central insulin resistance appears to be a risk factor for neurodegenerative disorders, these analogues might provide interesting avenues to protect against neurodegeneration and conditions such as Alzheimers and Parkinsons disease
The standard treatment for HFpEF includes sodium-glucose cotransporter 2 inhibitors (SGLT2i), such as empagliflozin and dapagliflozin, supported by the EMPEROR-Preserved (2021) and DELIVER (2022) trials [7, 8]
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