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2020;15(4): e0232357

The primary consideration for extended use is whether the therapeutic goal tissue repair, metabolic optimization has been achieved, or whether ongoing use serves a maintenance function

Peptides: Tesamorelin, AOD9604, Tirzepatide (GLP-1 agonist) Tesamorelin is FDA-approved to reduce visceral adipose tissue (VAT) in HIV-associated lipodystrophy, but its fat-burning effects also appear in non-HIV populations AOD9604 is a modified fragment of human GH (176191) shown in animal and early human trials to enhance lipolysis without altering blood sugar or cortisol Tirzepatide , while technically a GLP-1/GIP agonist , is now frequently stacked with peptides in clinical practice to accelerate fat loss and appetite control

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