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GPx, Glutation peroxidase

H., Jiawan, V

*Cytokine regulation: GSH modulates the production of pro-inflammatory cytokines including IL-1, IL-6, TNF-, and IFN- - all of which are elevated in Hashimoto's thyroiditis and Graves' disease B-cell antibody production: Oxidative stress promotes B-cell activation and autoantibody production

Common triggers include: Foods : histamine-rich foods (aged cheese, alcohol), fermented foods, shellfish Temperature extremes Exercise or physical pressure Environmental toxins Emotional stress Infections (viral, bacterial, parasitic) Medications : NSAIDs, opioids, certain anesthetics Hormonal shifts (e.g., during menstruation) Understanding personal triggers is essential to managing MCAS successfully