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Impaired anti-oxidant defense in G6PD-deficient erythrocytes makes them vulnerable to early membrane damage and ultimately phagocytosis when infected with malaria 5

Macaulay et al., 2022), and glucose uptake in the brain (Yamaguchi et al., 1997

The Journal of Nutrition, 134(3), 489-492

Fatigue accompanied by anhedonia, sleep disturbances, or changes in appetite beyond those expected from the medication warrants evaluation for depression, potentially using validated screening tools like the PHQ-9