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Body composition changes from improved fat oxidation develop over 48 weeks of consistent supplementation alongside a caloric deficit and regular exercise
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Were surrounded by easily accessible, affordable and delicious food, and busy lives mean that finding the time and willpower for exercise is hard
In the presence of carnitine, however, carnitine palmitoyltransferase-I , located in the outer mitochondrial membrane, converts long-chain acyl-CoA to acylcarnitine , which is able to penetrate the inner membrane and gain access to the -oxidation system of enzymes (Figure 221)
This difference in experience timeline is clinically useful
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