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It imposes a significant public health epidemic that has progressively worsened over the past semi-centennial

According to Grand View Research, the global insect repellent market size was valued at USD 2.8 billion in 2023 and is projected to grow at a CAGR of 7.4% from 2024 to 2030 , with bug repellent creams gaining traction due to their targeted application and long-lasting protection

4,14,16,24 Gastrointestinal side effects , including nausea and vomiting at higher doses, are by far most common, 25 and a reason for discontinuation of treatment

The sensitivity analysis (individuals with BMI 30 kg/m 2 ) generally reinforced findings from the BMI 27 kg/m 2 population, with both GLP-1 RAs demonstrating consistent associations with better ocular outcomes compared to traditional anti-obesity medications (Fig