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Overall Health : A persons overall health and the presence of any underlying medical conditions can affect the absorption and utilization of Vitamin B12

The risk of renal adverse reactions was increased in patients with a history of renal impairment (the weight management trials included 65 patients with a history of moderate or severe renal impairment at baseline), and occurred more frequently during dose titration

This is concerning because different "normal" but suboptimal micronutrient levels (also called marginal deficiencies or inadequacies) have been associated with various chronic health conditions, including cardiovascular disease, cancers, and stroke

Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research