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Various substituent groups decorating the EPT nucleus are key to modulating the toxicity of trichothecenes and based on these substitution patterns, trichothecenes can be sub-classified into four groups designated Type AD

Negative psychological stress has been found to increase the risk of asthma attacks in children (Liu et al., 2002), characterized by a high number of eosinophils in the sputum, EDN, IL-5 (Ritz and Steptoe, 2000), as well as decreased lung function during period of stress (Von Leupoldt et al., 2006)

In case of small number of samples that must be analyzed it might not be that important, however, when we look at the number of samples used for meta-analyses involving thousands of individuals the savings of time and laboratory single-use materials seem to be more spectacular

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