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Importantly, MRGPX2, previously known as MrgX2, can be stimulated by antimicrobial host defense peptides such as -defensins and the cathelicidin LL-37 [110], neuropeptides such as substance P [109] and vasoactive intestinal peptide, major basic protein, eosinophil peroxidase, and several peptidergic drugs [10, 11]

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