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Recent research shows that for people with long-term psychiatric illnesses, such as major depressive disorder, bipolar disorder, or schizophrenia, there are structural changes that take place in the brain.[ref] For me, the mental image is that neurotransmitters are acting like software, and altering the software code can alter mood

Ballas N, Grunseich C, Lu DD, Speh JC, Mandel G

NF-kappaB ist ein zentraler Transkriptionsfaktor, der die Expression hunderter entzuendungsfoerdernder Gene steuert

Ultrastructural analysis showed abundant electron-dense granular deposits and electron-dense lamellate lipid-like deposits that formed concentric bodies (zebra bodies) in the cytoplasm of podocytes and tubules