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This suggests a temporary effect on blood pressure regulation or hydration status rather than a direct neurological impact
[6] The American Association of Clinical Endocrinology (AACE) guidelines for obesity management similarly recommend comprehensive metabolic evaluation prior to weight loss pharmacotherapy, including thyroid assessment when clinically indicated
It is important to distinguish between dark urine caused by concentration (which appears deep yellow to amber and clears with increased fluid intake) and abnormal pigmentation suggesting pathology (such as tea-coloured urine indicating bilirubin, or red-brown urine suggesting blood or myoglobin)
Green et al., 2002)
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